Welcome to Institute of Genomics
Genoscope Home Page
The CNRGH is the French national research center which enables a response to scientific questions necessitating high throughput sequencing and genotyping thanks to the development and deployment of innovative integrated technologies. The organization of the CNRGH enables optimization of genetic and genomic research on human diseases by creating indispensable links between cohort constitution (DNA samples), identification of the responsible genes, and study of the transcriptome and epigenome.
List of the main projects of the Institut de Génomique
The Sequencing Laboratory assumes projects from receipt of the samples through validation of the raw sequences. Sequencing is ensured by second-generation very high-throughput sequencers. The machines enable throughput enabling whole-genome sequencing in a limited timeframe.
The projects implemented by the Sequencing Laboratory are essentially large-scale projects accepted following a Genoscope call for projects and, more recently, since 2012, France Génomique "Major sequencing projects, option Biodiversity" calls for projects. The Sequencing Laboratory also assumes all its own projects managed by the Genoscope scientific teams.
The projects currently ongoing cover a large panel of microorganisms, for example:
- Resequencing: unicellular fungi such as the yeast Saccharomyces cerevisiae or plants such as rice (genus: Oryza),
- De novo sequencing of protists (Paramecia), animal organisms such as Lymnaea (genus: Lymnaea) or plant organisms such as wheat (genus: Triticum),
- Sequencing of the transcriptomes of eukaryotic organisms such as oak (genus: Quercus),
- Metagenomic and metatranscriptomic projects (projects: Tara Oceans, biodiversity of French soil)
- Sequencing projects for the genome of the Périgord black truffle and Ectocarpus genome.
- 1002 yeast genomes, biodiversity of Alpine plants.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.