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The CNRGH is the French national research center which enables a response to scientific questions necessitating high throughput sequencing and genotyping thanks to the development and deployment of innovative integrated technologies. The organization of the CNRGH enables optimization of genetic and genomic research on human diseases by creating indispensable links between cohort constitution (DNA samples), identification of the responsible genes, and study of the transcriptome and epigenome.
List of the main projects of the Institut de Génomique
The MetaTAXOMIC-RMQS project is designed to characterize the bacterial taxonomic diversity of French soils using the Network for the Measurement of Soil Quality (RMQS). The network consists of 2200 soil samples from throughout France with very precise physicochemical and environmental characterization for each sample. Telluric bacterial diversity was analyzed using massive sequencing techniques (pyrosequencing) for the taxonomic genes (rrs) directly from the DNA extracted from the soil. The project enables:
MetaTAXOMIC-RMQS is positioned as a « basic research project » while there are also parallel technical objectives, which consist in developing bioinformatics and statistical tools enabling high-throughput analysis of taxonomic sequences and their provision to the scientific community via certain platforms (GenoSol, GenoTool, Genoscope, etc.). The operational objectives are as follows:
Laboratories involved: Laboratory of molecular biology methods for genomics, Sequencing laboratory
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.